O-GlcNAcylation Inhibition Upregulates Connexin43 Expression in the Endothelium to Protect the Tight Junction Barrier in Diabetic Retinopathy

PURPOSE: This study aimed to investigate the effects of O-linked N-acetylglucosamine modification (O-GlcNAcylation) on connexin43 (Cx43) expression and its subsequent effects on tight junction properties in diabetic retinopathy (DR). METHODS: O-GlcNAcylation levels in primary human retinal vascular...

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Detalles Bibliográficos
Autores principales: Liu, Guodong, Feng, Le, Liu, Xiaoqiang, Gao, Peng, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Physiology and Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668625/
https://www.ncbi.nlm.nih.gov/pubmed/37982762
http://dx.doi.org/10.1167/iovs.64.14.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668625/
https://www.ncbi.nlm.nih.gov/pubmed/37982762
http://dx.doi.org/10.1167/iovs.64.14.30

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