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Enhancing the Antifungal Efficacy of Fluconazole with a Diterpene: Abietic Acid as a Promising Adjuvant to Combat Antifungal Resistance in Candida spp.

The increasing antifungal resistance rates against conventional drugs reveal the urgent need to search for new therapeutic alternatives. In this context, natural bioactive compounds have a critical role in antifungal drug development. Since evidence demonstrates that abietic acid, a diterpene found...

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Detalles Bibliográficos
Autores principales: de Lima Silva, Maria Gabriely, de Lima, Luciene Ferreira, Alencar Fonseca, Victor Juno, Santos da Silva, Lucas Yure, Calixto Donelardy, Ana Cecília, de Almeida, Ray Silva, de Morais Oliveira-Tintino, Cícera Datiane, Pereira Bezerra Martins, Anita Oliveira Brito, Ribeiro-Filho, Jaime, Bezerra Morais-Braga, Maria Flaviana, Tintino, Saulo Relison, Alencar de Menezes, Irwin Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668680/
https://www.ncbi.nlm.nih.gov/pubmed/37998767
http://dx.doi.org/10.3390/antibiotics12111565