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Real-Life Vancomycin Therapeutic Drug Monitoring in Coagulase-Negative Staphylococcal Bacteremia in Neonatal and Pediatric Intensive Care Unit: Are We Underestimating Augmented Renal Clearance?

Bloodstream infections (BSI) from coagulase-negative-staphylococci (CoNS) are among the most frequent healthcare-related infections. Their treatment involves the use of vancomycin, a molecule whose optimal pharmacokinetic/pharmacodynamic (PK/PD) target for efficacy and safety is an area-under-curve/...

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Detalles Bibliográficos
Autores principales: Sette, Claudia, Mariani, Marcello, Grasselli, Luca, Mesini, Alessio, Saffioti, Carolina, Russo, Chiara, Bandettini, Roberto, Moscatelli, Andrea, Ramenghi, Luca A., Castagnola, Elio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668724/
https://www.ncbi.nlm.nih.gov/pubmed/37998768
http://dx.doi.org/10.3390/antibiotics12111566