Inoculum-Based Dosing: A Novel Concept for Combining Time with Concentration-Dependent Antibiotics to Optimize Clinical and Microbiological Outcomes in Severe Gram Negative Sepsis

Certain classes of antibiotics show “concentration dependent” antimicrobial activity; higher concentrations result in increased bacterial killing rates, in contrast to “time dependent antibiotics”, which show antimicrobial activity that depends on the time that antibiotic concentrations remain above...

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Detalles Bibliográficos
Autores principales: Tilanus, Alwin, Drusano, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668771/
https://www.ncbi.nlm.nih.gov/pubmed/37998783
http://dx.doi.org/10.3390/antibiotics12111581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668771/
https://www.ncbi.nlm.nih.gov/pubmed/37998783
http://dx.doi.org/10.3390/antibiotics12111581

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