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Multi-Oxidant Environment as a Suicidal Inhibitor of Myeloperoxidase

Tissue inflammation drives the infiltration of innate immune cells that generate reactive species to kill bacteria and recruit adaptive immune cells. Neutrophil activation fosters the release of myeloperoxidase (MPO) enzyme, a heme-containing protein generating hypochlorous acid (HOCl) from hydrogen...

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Detalles Bibliográficos
Autores principales: Clemen, Ramona, Minkus, Lara, Singer, Debora, Schulan, Paul, von Woedtke, Thomas, Wende, Kristian, Bekeschus, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668958/
https://www.ncbi.nlm.nih.gov/pubmed/38001789
http://dx.doi.org/10.3390/antiox12111936