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LEO1 Is Required for Efficient Entry into Quiescence, Control of H3K9 Methylation and Gene Expression in Human Fibroblasts

(1) Background: The LEO1 (Left open reading frame 1) protein is a conserved subunit of the PAF1C complex (RNA polymerase II-associated factor 1 complex). PAF1C has well-established mechanistic functions in elongation of transcription and RNA processing. We previously showed, in fission yeast, that L...

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Detalles Bibliográficos
Autores principales: Laurent, Marc, Cordeddu, Lina, Zahedi, Yasaman, Ekwall, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668985/
https://www.ncbi.nlm.nih.gov/pubmed/38002344
http://dx.doi.org/10.3390/biom13111662