The Coumarin-Derivative Esculetin Protects against Lipotoxicity in Primary Rat Hepatocytes via Attenuating JNK-Mediated Oxidative Stress and Attenuates Free Fatty Acid-Induced Lipid Accumulation

Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-associated fatty liver disease (MAFLD). However, the mechanisms underlying their beneficial effects remain unclear. In the present study, we explored the potential of the coumarin derivate esculetin in MAFLD, fo...

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Detalles Bibliográficos
Autores principales: Xia, Mengmeng, Wu, Zongmei, Wang, Junyu, Buist-Homan, Manon, Moshage, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669015/
https://www.ncbi.nlm.nih.gov/pubmed/38001774
http://dx.doi.org/10.3390/antiox12111922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669015/
https://www.ncbi.nlm.nih.gov/pubmed/38001774
http://dx.doi.org/10.3390/antiox12111922

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