Probing the Proton-Gated ASIC Channels Using Tetraalkylammonium Ions

The action of tetraalkylammonium ions, from tetrametylammonium (TMA) to tetrapentylammonium (TPtA), on the recombinant and native acid-sensing ion channels (ASICs) was studied using the patch-clamp approach. The responses of ASIC1a, ASIC2a, and native heteromeric ASICs were inhibited by TPtA. The pe...

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Detalles Bibliográficos
Autores principales: Evlanenkov, Konstantin K., Nikolaev, Maxim V., Potapieva, Natalia N., Bolshakov, Konstantin V., Tikhonov, Denis B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669046/
https://www.ncbi.nlm.nih.gov/pubmed/38002313
http://dx.doi.org/10.3390/biom13111631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669046/
https://www.ncbi.nlm.nih.gov/pubmed/38002313
http://dx.doi.org/10.3390/biom13111631

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