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The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence

Retrotransposons have played an important role in evolution through their transposable activity. The largest and the only currently active human group of mobile DNAs are the LINE-1 retrotransposons. The ectopic expression of LINE-1 has been correlated with genomic instability. Narrow-band ultraviole...

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Detalles Bibliográficos
Autores principales: Touma, Fadi, Lambert, Marine, Martínez Villarreal, Amelia, Gantchev, Jennifer, Ramchatesingh, Brandon, Litvinov, Ivan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669206/
https://www.ncbi.nlm.nih.gov/pubmed/38002016
http://dx.doi.org/10.3390/biomedicines11113017