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The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence
Retrotransposons have played an important role in evolution through their transposable activity. The largest and the only currently active human group of mobile DNAs are the LINE-1 retrotransposons. The ectopic expression of LINE-1 has been correlated with genomic instability. Narrow-band ultraviole...
Autores principales: | Touma, Fadi, Lambert, Marine, Martínez Villarreal, Amelia, Gantchev, Jennifer, Ramchatesingh, Brandon, Litvinov, Ivan V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669206/ https://www.ncbi.nlm.nih.gov/pubmed/38002016 http://dx.doi.org/10.3390/biomedicines11113017 |
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