Astrocytic Nrf2 Mediates the Neuroprotective and Anti-Inflammatory Effects of Nootkatone in an MPTP-Induced Parkinson’s Disease Mouse Model

This study aims to investigate the neuroprotective effects of nootkatone (NKT), a sesquiterpenoid compound isolated from grapefruit, in an MPTP-induced Parkinson’s disease (PD) mouse model. NKT restored MPTP-induced motor impairment and dopaminergic neuronal loss and increased the expression of neur...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jung-Eun, Leem, Yea-Hyun, Park, Jin-Sun, Kim, Seong-Eun, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669233/
https://www.ncbi.nlm.nih.gov/pubmed/38001852
http://dx.doi.org/10.3390/antiox12111999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669233/
https://www.ncbi.nlm.nih.gov/pubmed/38001852
http://dx.doi.org/10.3390/antiox12111999

Ejemplares similares