High-Altitude Hypoxia Induces Excessive Erythrocytosis in Mice via Upregulation of the Intestinal HIF2a/Iron-Metabolism Pathway

Excessive erythrocytosis (EE) is a preclinical form of chronic mountain sickness (CMS). The dysregulation of iron metabolism in high-altitude hypoxia may induce EE. The intestinal hypoxia-inducible factor 2 alpha (HIF2a) regulates the genes involved in iron metabolism. Considering these findings, we...

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Detalles Bibliográficos
Autores principales: Zhou, Sisi, Yan, Jun, Song, Kang, Ge, Ri-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669251/
https://www.ncbi.nlm.nih.gov/pubmed/38001992
http://dx.doi.org/10.3390/biomedicines11112992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669251/
https://www.ncbi.nlm.nih.gov/pubmed/38001992
http://dx.doi.org/10.3390/biomedicines11112992

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