Cargando…

Sexually Dimorphic Effects of Histamine Degradation by Enteric Glial Histamine N-Methyltransferase (HNMT) on Visceral Hypersensitivity

Histamine is a neuromodulator that affects gut motility and visceral sensitivity through intrinsic and extrinsic neural pathways, yet the mechanisms regulating histamine availability in these pathways remain poorly understood. Here, we show that enteric glia contribute to histamine clearance in the...

Descripción completa

Detalles Bibliográficos
Autores principales: McClain, Jonathon L., Morales-Soto, Wilmarie, Gonzales, Jacques, Parmar, Visha, Demireva, Elena Y., Gulbransen, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669271/
https://www.ncbi.nlm.nih.gov/pubmed/38002333
http://dx.doi.org/10.3390/biom13111651