Targeting Pro-Oxidant Iron with Exogenously Administered Apotransferrin Provides Benefits Associated with Changes in Crucial Cellular Iron Gate Protein TfR in a Model of Intracerebral Hemorrhagic Stroke in Mice

We have previously demonstrated that the post-stroke administration of iron-free transferrin (apotransferrin, ATf) is beneficial in different models of ischemic stroke (IS) through the inhibition of the neuronal uptake of pro-oxidant iron. In the present study, we asked whether ATf is safe and also...

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Detalles Bibliográficos
Autores principales: García-Serran, Alexia, Ordoño, Jesús, DeGregorio-Rocasolano, Núria, Melià-Sorolla, Marc, Odendaal, Karla, Martí-Sistac, Octavi, Gasull, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669272/
https://www.ncbi.nlm.nih.gov/pubmed/38001798
http://dx.doi.org/10.3390/antiox12111945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669272/
https://www.ncbi.nlm.nih.gov/pubmed/38001798
http://dx.doi.org/10.3390/antiox12111945

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