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Therapeutic Dosage of Antipsychotic Drug Aripiprazole Induces Persistent Mitochondrial Hyperpolarisation, Moderate Oxidative Stress in Liver Cells, and Haemolysis

Aripiprazole has fewer metabolic side effects than other antipsychotics; however, there are some severe ones in the liver, leading to drug-induced liver injury. Repeated treatment with aripiprazole affects cell division. Since this process requires a lot of energy, we decided to investigate the impa...

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Detalles Bibliográficos
Autores principales: Pirc Marolt, Tinkara, Kramar, Barbara, Vovk, Andrej, Podgornik, Helena, Šuput, Dušan, Milisav, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669280/
https://www.ncbi.nlm.nih.gov/pubmed/38001783
http://dx.doi.org/10.3390/antiox12111930