Cargando…

Therapeutic Dosage of Antipsychotic Drug Aripiprazole Induces Persistent Mitochondrial Hyperpolarisation, Moderate Oxidative Stress in Liver Cells, and Haemolysis

Aripiprazole has fewer metabolic side effects than other antipsychotics; however, there are some severe ones in the liver, leading to drug-induced liver injury. Repeated treatment with aripiprazole affects cell division. Since this process requires a lot of energy, we decided to investigate the impa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pirc Marolt, Tinkara, Kramar, Barbara, Vovk, Andrej, Podgornik, Helena, Šuput, Dušan, Milisav, Irina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669280/ https://www.ncbi.nlm.nih.gov/pubmed/38001783 http://dx.doi.org/10.3390/antiox12111930

Ejemplares similares

Antipsychotic Drug Aripiprazole Protects Liver Cells from Oxidative Stress
por: Kramar, Barbara, et al.
Publicado: (2022)

Aripiprazole reduces liver cell division
por: Pirc Marolt, Tinkara, et al.
Publicado: (2020)

Medical and Dietary Uses of N-Acetylcysteine
por: Šalamon, Špela, et al.
Publicado: (2019)

Differential p16 expression levels in the liver, hepatocytes and hepatocellular cell lines
por: Kramar, Barbara, et al.
Publicado: (2021)

Procaspase-9 is attached to the mitochondrial outer membrane in the early stages of apoptosis
por: Milisav, Irina, et al.
Publicado: (2007)

Achieving the Balance between ROS and Antioxidants: When to Use the Synthetic Antioxidants
por: Poljsak, Borut, et al.
Publicado: (2013)

Adaptive Response, Evidence of Cross-Resistance and Its Potential Clinical Use
por: Milisav, Irina, et al.
Publicado: (2012)

Unfolded Protein Response and Macroautophagy in Alzheimer’s, Parkinson’s and Prion Diseases
por: Milisav, Irina, et al.
Publicado: (2015)

Beneficial Role of ROS in Cell Survival: Moderate Increases in H(2)O(2) Production Induced by Hepatocyte Isolation Mediate Stress Adaptation and Enhanced Survival
por: Miller, Izak Patrik, et al.
Publicado: (2019)

Effects of NH(4)CL application and removal on astrocytes and endothelial cells
por: Bartolić, Miha, et al.
Publicado: (2016)

DMSO modulates the pathway of apoptosis triggering
por: Banič, Blaž, et al.
Publicado: (2011)

Semi-Automatic Signature-Based Segmentation Method for Quantification of Neuromelanin in Substantia Nigra
por: Zupan, Gašper, et al.
Publicado: (2019)

Antipsychotic treatments for the elderly: efficacy and safety of aripiprazole
por: Kohen, Izchak, et al.
Publicado: (2010)

Predictors of Success of Inpatient Pulmonary Rehabilitation Program in COPD Patients
por: Hafner, Tomaž, et al.
Publicado: (2023)

Magnetic Resonance Imaging for Rapid Screening for the Nephrotoxic and Hepatotoxic Effects of Microcystins
por: Milutinović, Aleksandra, et al.
Publicado: (2013)

Detection of metabolic syndrome burden in healthy young adults may enable timely introduction of disease prevention
por: Šoštarič, Anja, et al.
Publicado: (2019)

Cholesterol and Haemolysis
Publicado: (1915)

Reversal of symptomatic antipsychotic-induced hyperprolactinemia with addition of aripiprazole
por: Kotorki, Paraskevi, et al.
Publicado: (2010)

Successful treatment of a prolactinoma with the antipsychotic drug aripiprazole
por: Bakker, Ilse C A, et al.
Publicado: (2016)

Mycoplasma pneumonia with persistent lymphadenopathy and severe cold agglutinin haemolysis
por: Shah, Mit, et al.
Publicado: (2016)

Does intervention with GLP-1 receptor agonist semaglutide modulate perception of sweet taste in women with obesity: study protocol of a randomized, single-blinded, placebo-controlled clinical trial
por: Jensterle, Mojca, et al.
Publicado: (2021)

TARC: Turkish aripiprazole consensus report- Aripiprazole use and switching from other antipsychotics to aripiprazole- consensus recommendations by a Turkish multidisciplinary panel
por: Veznedaroglu, Baybars, et al.
Publicado: (2018)

Acute Hyperglycemia and Spatial Working Memory in Adolescents With Type 1 Diabetes
por: Šuput Omladič, Jasna, et al.
Publicado: (2020)

Add-on Aripiprazole for Atypical Antipsychotic-induced, Clinically Significant Hyperprolactinemia
por: Raveendranthan, Dhanya, et al.
Publicado: (2018)

Antipsychotics dosage and antiparkinsonian prescriptions
por: Acquaviva, Eric, et al.
Publicado: (2007)

Theoretical Modelling of Photoswitching of Hyperpolarisabilities in Ruthenium Complexes
por: Coe, Benjamin J, et al.
Publicado: (2013)

Quantum probe hyperpolarisation of molecular nuclear spins
por: Broadway, David A., et al.
Publicado: (2018)

Direct and indirect hyperpolarisation of amines using parahydrogen
por: Iali, Wissam, et al.
Publicado: (2018)

New Cocrystals of Antipsychotic Drug Aripiprazole: Decreasing the Dissolution through Cocrystallization
por: Liu, Wenwen, et al.
Publicado: (2021)

Dosage of antipsychotics in China routine practice
por: Zhang, T., et al.
Publicado: (2021)

Blackwater Fever, Hæmolysis and Quinine
por: MacGilchrist, A. C.
Publicado: (1909)

Haemolysis as Influence & Interference Factor
por: Thomas, L.
Publicado: (2002)

Antimicrobial mechanisms due to hyperpolarisation induced by nanoporous Au
por: Miyazawa, Naoki, et al.
Publicado: (2018)

Long-lived states to sustain SABRE hyperpolarised magnetisation
por: Roy, Soumya S., et al.
Publicado: (2016)

Population Pharmacokinetic Analysis and Model-Based Simulations of Aripiprazole for a 1-Day Initiation Regimen for the Long-Acting Antipsychotic Aripiprazole Lauroxil
por: Hard, Marjie L., et al.
Publicado: (2018)

Pharmacokinetics and safety of deltoid or gluteal injection of aripiprazole lauroxil NanoCrystal(®) Dispersion used for initiation of the long-acting antipsychotic aripiprazole lauroxil
por: Hard, Marjie L., et al.
Publicado: (2019)

A Comment on “Add-on Aripiprazole for Atypical Antipsychotic-induced, Clinically Significant Hyperprolactinemia”
por: Naguy, Ahmed
Publicado: (2018)

Aripiprazole Lauroxil: Pharmacokinetic Profile of This Long-Acting Injectable Antipsychotic in Persons With Schizophrenia
por: Hard, Marjie L., et al.
Publicado: (2017)

Serum prolactin levels and sexual dysfunction in patients with schizophrenia treated with antipsychotics: comparison between aripiprazole and other atypical antipsychotics
por: Kirino, Eiji
Publicado: (2017)

The Hæmolysis of Erythrocytes in Solutions of the Alkali Halides
por: Hendry, Edward B.
Publicado: (1948)

Cannot write session to /tmp/vufind_sessions/sess_e20c5bb0p63ce1q8400i4k32sj