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GSK2606414 Sensitizes ABCG2-Overexpressing Multidrug-Resistant Colorectal Cancer Cells to Chemotherapeutic Drugs

Colorectal cancer is a common malignant tumor. A major factor in the high mortality rate of colorectal cancer is the emergence of multidrug resistance (MDR). Overexpression of the ABCG2 gene in cancer cells directly leads to MDR. Finding new inhibitors of ABCG2 may be an effective way to overcome dr...

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Detalles Bibliográficos
Autores principales: Yu, Ze-Zhong, Xu, Bu-Qing, Wang, Ying-Ying, Zhang, Peng-Wei, Shu, Yu-Bin, Shi, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669325/
https://www.ncbi.nlm.nih.gov/pubmed/38002103
http://dx.doi.org/10.3390/biomedicines11113103