Amyloid β-Oligomers Inhibit the Nuclear Ca(2+) Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons

Hippocampal neuronal activity generates dendritic and somatic Ca(2+) signals, which, depending on stimulus intensity, rapidly propagate to the nucleus and induce the expression of transcription factors and genes with crucial roles in cognitive functions. Soluble amyloid-beta oligomers (AβOs), the ma...

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Detalles Bibliográficos
Autores principales: Lobos, Pedro, Vega-Vásquez, Ignacio, Bruna, Barbara, Gleitze, Silvia, Toledo, Jorge, Härtel, Steffen, Hidalgo, Cecilia, Paula-Lima, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669355/
https://www.ncbi.nlm.nih.gov/pubmed/38001825
http://dx.doi.org/10.3390/antiox12111972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669355/
https://www.ncbi.nlm.nih.gov/pubmed/38001825
http://dx.doi.org/10.3390/antiox12111972

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