Elevated Levels of Mislocalised, Constitutive Ras Signalling Can Drive Quiescence by Uncoupling Cell-Cycle Regulation from Metabolic Homeostasis

The small GTPase Ras plays an important role in connecting external and internal signalling cues to cell fate in eukaryotic cells. As such, the loss of RAS regulation, localisation, or expression level can drive changes in cell behaviour and fate. Post-translational modifications and expression leve...

Descripción completa

Detalles Bibliográficos
Autores principales: Piper-Brown, Elliot, Dresel, Fiona, Badr, Eman, Gourlay, Campbell W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669370/
https://www.ncbi.nlm.nih.gov/pubmed/38002301
http://dx.doi.org/10.3390/biom13111619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669370/
https://www.ncbi.nlm.nih.gov/pubmed/38002301
http://dx.doi.org/10.3390/biom13111619

Ejemplares similares