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Effects of Combinations of Untranslated-Region Sequences on Translation of mRNA

mRNA-based therapeutics have been found to be a promising treatment strategy in immunotherapy, gene therapy, and cancer treatments. Effectiveness of mRNA therapeutics depends on the level and duration of a desired protein’s expression, which is determined by various cis- and trans-regulatory element...

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Detalles Bibliográficos
Autores principales: Kirshina, Anna, Vasileva, Olga, Kunyk, Dmitry, Seregina, Kristina, Muslimov, Albert, Ivanov, Roman, Reshetnikov, Vasiliy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669451/
https://www.ncbi.nlm.nih.gov/pubmed/38002359
http://dx.doi.org/10.3390/biom13111677