Cargando…
Effects of Combinations of Untranslated-Region Sequences on Translation of mRNA
mRNA-based therapeutics have been found to be a promising treatment strategy in immunotherapy, gene therapy, and cancer treatments. Effectiveness of mRNA therapeutics depends on the level and duration of a desired protein’s expression, which is determined by various cis- and trans-regulatory element...
Autores principales: | Kirshina, Anna, Vasileva, Olga, Kunyk, Dmitry, Seregina, Kristina, Muslimov, Albert, Ivanov, Roman, Reshetnikov, Vasiliy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669451/ https://www.ncbi.nlm.nih.gov/pubmed/38002359 http://dx.doi.org/10.3390/biom13111677 |
Ejemplares similares
-
The Dual Role of the Innate Immune System in the Effectiveness of mRNA Therapeutics
por: Muslimov, Albert, et al.
Publicado: (2023) -
Challenging the Roles of NSP3 and Untranslated Regions in Rotavirus mRNA Translation
por: Gratia, Matthieu, et al.
Publicado: (2016) -
Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA
por: Asrani, Kirtika H., et al.
Publicado: (2018) -
Influence of untranslated regions on retroviral mRNA transfer and expression
por: Prel, Anne, et al.
Publicado: (2013) -
Untranslated regions of brain-derived neurotrophic factor mRNA control its translatability and subcellular localization
por: Lekk, Ingrid, et al.
Publicado: (2023)