Lysosomal-Cleavable Peptide Linkers in Antibody–Drug Conjugates

Antibody–drug Conjugates (ADCs) are a powerful therapeutic modality for cancer treatment. ADCs are multi-functional biologics in which a disease-targeting antibody is conjugated to an effector payload molecule via a linker. The success of currently used ADCs has been largely attributed to the develo...

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Detalles Bibliográficos
Autores principales: Balamkundu, Seetharamsing, Liu, Chuan-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669454/
https://www.ncbi.nlm.nih.gov/pubmed/38002080
http://dx.doi.org/10.3390/biomedicines11113080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669454/
https://www.ncbi.nlm.nih.gov/pubmed/38002080
http://dx.doi.org/10.3390/biomedicines11113080

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