Superoxide-Mediated Upregulation of MMP9 Participates in BMPR2 Destabilization and Pulmonary Hypertension Development

Background and Aims: we previously reported in studies on organoid-cultured bovine pulmonary arteries that pulmonary hypertension (PH) conditions of exposure to hypoxia or endothelin-1 caused a loss of a cartilage oligomeric matrix protein (COMP) stabilization of bone morphogenetic protein receptor-...

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Detalles Bibliográficos
Autores principales: Alruwaili, Norah, Kandhi, Sharath, Froogh, Ghezal, Kelly, Melissa R., Sun, Dong, Wolin, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669489/
https://www.ncbi.nlm.nih.gov/pubmed/38001814
http://dx.doi.org/10.3390/antiox12111961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669489/
https://www.ncbi.nlm.nih.gov/pubmed/38001814
http://dx.doi.org/10.3390/antiox12111961

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