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Superoxide-Mediated Upregulation of MMP9 Participates in BMPR2 Destabilization and Pulmonary Hypertension Development
Background and Aims: we previously reported in studies on organoid-cultured bovine pulmonary arteries that pulmonary hypertension (PH) conditions of exposure to hypoxia or endothelin-1 caused a loss of a cartilage oligomeric matrix protein (COMP) stabilization of bone morphogenetic protein receptor-...
Autores principales: | Alruwaili, Norah, Kandhi, Sharath, Froogh, Ghezal, Kelly, Melissa R., Sun, Dong, Wolin, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669489/ https://www.ncbi.nlm.nih.gov/pubmed/38001814 http://dx.doi.org/10.3390/antiox12111961 |
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