Cargando…

Characterization of a Human Neuronal Culture System for the Study of Cofilin–Actin Rod Pathology

Cofilactin rod pathology, which can initiate synapse loss, has been extensively studied in rodent neurons, hippocampal slices, and in vivo mouse models of human neurodegenerative diseases such as Alzheimer’s disease (AD). In these systems, rod formation induced by disease-associated factors, such as...

Descripción completa

Detalles Bibliográficos
Autores principales: Tahtamouni, Lubna H., Alderfer, Sydney A., Kuhn, Thomas B., Minamide, Laurie S., Chanda, Soham, Ruff, Michael R., Bamburg, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669520/
https://www.ncbi.nlm.nih.gov/pubmed/38001943
http://dx.doi.org/10.3390/biomedicines11112942