Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody

Monoclonal antibody-based therapy has shown efficacy against cancer, autoimmune, infectious, and inflammatory diseases. Multispecific antibodies (MsAbs), including trispecifics (tsAbs), offer enhanced therapeutic potential by targeting different epitopes. However, when co-expressed from three or mor...

Descripción completa

Detalles Bibliográficos
Autores principales: Sebastião, Maria João, Hoffman, Michael, Escandell, José, Tousi, Fatemeh, Zhang, Jin, Figueroa, Bruno, DeMaria, Christine, Gomes-Alves, Patrícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669571/
https://www.ncbi.nlm.nih.gov/pubmed/38001891
http://dx.doi.org/10.3390/biomedicines11112890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669571/
https://www.ncbi.nlm.nih.gov/pubmed/38001891
http://dx.doi.org/10.3390/biomedicines11112890

Ejemplares similares