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Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody
Monoclonal antibody-based therapy has shown efficacy against cancer, autoimmune, infectious, and inflammatory diseases. Multispecific antibodies (MsAbs), including trispecifics (tsAbs), offer enhanced therapeutic potential by targeting different epitopes. However, when co-expressed from three or mor...
Autores principales: | Sebastião, Maria João, Hoffman, Michael, Escandell, José, Tousi, Fatemeh, Zhang, Jin, Figueroa, Bruno, DeMaria, Christine, Gomes-Alves, Patrícia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669571/ https://www.ncbi.nlm.nih.gov/pubmed/38001891 http://dx.doi.org/10.3390/biomedicines11112890 |
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