Assessing Genetic Algorithm-Based Docking Protocols for Prediction of Heparin Oligosaccharide Binding Geometries onto Proteins

Although molecular docking has evolved dramatically over the years, its application to glycosaminoglycans (GAGs) has remained challenging because of their intrinsic flexibility, highly anionic character and rather ill-defined site of binding on proteins. GAGs have been treated as either fully “rigid...

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Detalles Bibliográficos
Autores principales: Holmes, Samuel G., Desai, Umesh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669598/
https://www.ncbi.nlm.nih.gov/pubmed/38002315
http://dx.doi.org/10.3390/biom13111633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669598/
https://www.ncbi.nlm.nih.gov/pubmed/38002315
http://dx.doi.org/10.3390/biom13111633

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