c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration

The endoplasmic reticulum is a subcellular organelle key in the control of synthesis, folding, and sorting of proteins. Under endoplasmic reticulum stress, an adaptative unfolded protein response is activated; however, if this activation is prolonged, cells can undergo cell death, in part due to oxi...

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Detalles Bibliográficos
Autores principales: Martinez, Alexis, Lamaizon, Cristian M., Valls, Cristian, Llambi, Fabien, Leal, Nancy, Fitzgerald, Patrick, Guy, Cliff, Kamiński, Marcin M., Inestrosa, Nibaldo C., van Zundert, Brigitte, Cancino, Gonzalo I., Dulcey, Andrés E., Zanlungo, Silvana, Marugan, Juan J., Hetz, Claudio, Green, Douglas R., Alvarez, Alejandra R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669615/
https://www.ncbi.nlm.nih.gov/pubmed/38001860
http://dx.doi.org/10.3390/antiox12112007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669615/
https://www.ncbi.nlm.nih.gov/pubmed/38001860
http://dx.doi.org/10.3390/antiox12112007

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