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c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration
The endoplasmic reticulum is a subcellular organelle key in the control of synthesis, folding, and sorting of proteins. Under endoplasmic reticulum stress, an adaptative unfolded protein response is activated; however, if this activation is prolonged, cells can undergo cell death, in part due to oxi...
Autores principales: | Martinez, Alexis, Lamaizon, Cristian M., Valls, Cristian, Llambi, Fabien, Leal, Nancy, Fitzgerald, Patrick, Guy, Cliff, Kamiński, Marcin M., Inestrosa, Nibaldo C., van Zundert, Brigitte, Cancino, Gonzalo I., Dulcey, Andrés E., Zanlungo, Silvana, Marugan, Juan J., Hetz, Claudio, Green, Douglas R., Alvarez, Alejandra R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669615/ https://www.ncbi.nlm.nih.gov/pubmed/38001860 http://dx.doi.org/10.3390/antiox12112007 |
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