The Combination of Radiation with PARP Inhibition Enhances Senescence and Sensitivity to the Senolytic, Navitoclax, in Triple Negative Breast Tumor Cells

Despite significant advances in the treatment of triple-negative breast cancer, this disease continues to pose a clinical challenge, with many patients ultimately suffering from relapse. Tumor cells that recover after entering into a state of senescence after chemotherapy or radiation have been show...

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Detalles Bibliográficos
Autores principales: Softah, Abrar, Alotaibi, Moureq R., Alhoshani, Ali R., Saleh, Tareq, Alhazzani, Khalid, Almutairi, Mashal M., AlRowis, Raed, Alshehri, Samiyah, Albekairy, Norah A., Harada, Hisashi, Boyd, Rowan, Chakraborty, Eesha, Gewirtz, David A., As Sobeai, Homood M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669784/
https://www.ncbi.nlm.nih.gov/pubmed/38002066
http://dx.doi.org/10.3390/biomedicines11113066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669784/
https://www.ncbi.nlm.nih.gov/pubmed/38002066
http://dx.doi.org/10.3390/biomedicines11113066

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