The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes

The dysfunction and selective loss of retinal ganglion cells (RGCs) is a known cause of vision loss in glaucoma and other neuropathies, where ocular hypertension (OHT) is the major risk factor. We investigated the impact of transient non-ischemic OHT spikes (spOHT) on RGC function and viability in v...

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Detalles Bibliográficos
Autores principales: Spurlock, Markus, An, Weijun, Reshetnikova, Galina, Wen, Rong, Wang, Hua, Braha, Michelle, Solis, Gabriela, Kurtenbach, Stefan, Galindez, Orlando J., de Rivero Vaccari, Juan Pablo, Chou, Tsung-Han, Porciatti, Vittorio, Shestopalov, Valery I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670000/
https://www.ncbi.nlm.nih.gov/pubmed/37998361
http://dx.doi.org/10.3390/cells12222626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670000/
https://www.ncbi.nlm.nih.gov/pubmed/37998361
http://dx.doi.org/10.3390/cells12222626

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