Cargando…

The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes

The dysfunction and selective loss of retinal ganglion cells (RGCs) is a known cause of vision loss in glaucoma and other neuropathies, where ocular hypertension (OHT) is the major risk factor. We investigated the impact of transient non-ischemic OHT spikes (spOHT) on RGC function and viability in v...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spurlock, Markus, An, Weijun, Reshetnikova, Galina, Wen, Rong, Wang, Hua, Braha, Michelle, Solis, Gabriela, Kurtenbach, Stefan, Galindez, Orlando J., de Rivero Vaccari, Juan Pablo, Chou, Tsung-Han, Porciatti, Vittorio, Shestopalov, Valery I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670000/ https://www.ncbi.nlm.nih.gov/pubmed/37998361 http://dx.doi.org/10.3390/cells12222626

Ejemplares similares

Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells
por: Dvoriantchikova, Galina, et al.
Publicado: (2018)

Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury
por: Pronin, Alexey, et al.
Publicado: (2019)

Retinal and cortical visual acuity in a common inbred albino mouse
por: Braha, Michelle, et al.
Publicado: (2021)

Modeling Retinal Ganglion Cell Dysfunction in Optic Neuropathies
por: Porciatti, Vittorio, et al.
Publicado: (2021)

Adaptable retinal ganglion cell function: assessing autoregulation of inner retina pathways
por: Chou, Tsung-Han, et al.
Publicado: (2020)

Diabetes Exacerbates the Intraocular Pressure-Independent Retinal Ganglion Cells Degeneration in the DBA/2J Model of Glaucoma
por: Amato, Rosario, et al.
Publicado: (2021)

Adaptation of retinal ganglion cell function during flickering light in the mouse
por: Chou, Tsung-Han, et al.
Publicado: (2019)

Compartmental Differences in Macular Retinal Ganglion Cell Function
por: Alba, Diego, et al.
Publicado: (2021)

Nicotinamide-Rich Diet in DBA/2J Mice Preserves Retinal Ganglion Cell Metabolic Function as Assessed by PERG Adaptation to Flicker
por: Chou, Tsung-Han, et al.
Publicado: (2020)

Protection of Pattern Electroretinogram and Retinal Ganglion Cells by Oncostatin M after Optic Nerve Injury
por: Xia, Xin, et al.
Publicado: (2014)

The Inflammasome in Times of COVID-19
por: de Rivero Vaccari, Juan Carlos, et al.
Publicado: (2020)

Inflammasome Proteins as Inflammatory Biomarkers of Age-Related Macular Degeneration
por: Weaver, Cailey, et al.
Publicado: (2020)

1α,25-dihydroxyvitamin D(3) protects retinal ganglion cells in glaucomatous mice
por: Lazzara, Francesca, et al.
Publicado: (2021)

The Inflammasome in Reproductive Biology: A Promising Target for Novel Therapies
por: de Rivero Vaccari, Juan Pablo
Publicado: (2020)

Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis
por: Brambilla, Roberta, et al.
Publicado: (2012)

Contribution of the inflammasome to inflammaging
por: Mejias, Nancy H., et al.
Publicado: (2018)

Inflammasome Proteins As Biomarkers of Multiple Sclerosis
por: Keane, Robert W., et al.
Publicado: (2018)

Inflammasome signaling proteins as biomarkers of COVID-19
por: Hadad, Roey, et al.
Publicado: (2023)

Using Noninvasive Electrophysiology to Determine Time Windows of Neuroprotection in Optic Neuropathies
por: Porciatti, Vittorio, et al.
Publicado: (2022)

Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets
por: Govindarajan, Vaidya, et al.
Publicado: (2020)

The Role of Non-canonical and Canonical Inflammasomes in Inflammaging
por: Cyr, Brianna, et al.
Publicado: (2022)

Met Receptor Subcellular Localization Depends on E-Cadherin Function
por: Reshetnikova, Galina
Publicado: (2007)

σ(2)R/TMEM97 in retinal ganglion cell degeneration
por: Wang, Hua, et al.
Publicado: (2022)

Carbon monoxide releasing molecule-3 inhibits inflammasome activation: A potential therapy for spinal cord injury
por: de Rivero Vaccari, Juan Pablo
Publicado: (2019)

Investigation of olfactory function in a Panx1 knock out mouse model
por: Kurtenbach, Stefan, et al.
Publicado: (2014)

The Inflammasome Signaling Proteins ASC and IL-18 as Biomarkers of Psoriasis
por: Forouzandeh, Mahtab, et al.
Publicado: (2020)

A Potential Compensatory Role of Panx3 in the VNO of a Panx1 Knock Out Mouse Model
por: Whyte-Fagundes, Paige, et al.
Publicado: (2018)

C57BL/6J, DBA/2J, and DBA/2J.Gpnmb(+) mice have different visual signal processing in the inner retina
por: Porciatti, Vittorio, et al.
Publicado: (2010)

Acidification changes affect the inflammasome in human nucleus pulposus cells
por: Brand, Frank J., et al.
Publicado: (2016)

Inflammasome activation in traumatic brain injury and Alzheimer’s disease
por: Johnson, Nathan H., et al.
Publicado: (2023)

Correction: Pannexin1 Stabilizes Synaptic Plasticity and Is Needed for Learning
por: Prochnow, Nora, et al.
Publicado: (2013)

Pannexin1 Stabilizes Synaptic Plasticity and Is Needed for Learning
por: Prochnow, Nora, et al.
Publicado: (2012)

Immune Responses in the Glaucomatous Retina: Regulation and Dynamics
por: Shestopalov, Valery I., et al.
Publicado: (2021)

Impact of aromatase absence on murine intraocular pressure and retinal ganglion cells
por: Chen, Xiaomin, et al.
Publicado: (2018)

Intraocular Pressure Elevation Compromises Retinal Ganglion Cell Light Adaptation
por: Tao, Xiaofeng, et al.
Publicado: (2020)

NLRP3 inflammasome in retinal ganglion cell loss in optic neuropathy
por: Feng, Liang, et al.
Publicado: (2016)

β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival
por: Santos, Andrea Rachelle C., et al.
Publicado: (2012)

Intracranial migration of intraocular silicone oil following repetitive head trauma
por: Zhong, Han, et al.
Publicado: (2019)

Inflammasome proteins as biomarkers of traumatic brain injury
por: Kerr, Nadine, et al.
Publicado: (2018)

Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats
por: Mawhinney, Lana J, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_6jff0419d4r9cu4j84u77hrels