Sustained Nrf2 Overexpression-Induced Metabolic Deregulation Can Be Attenuated by Modulating Insulin/Insulin-like Growth Factor Signaling

The modulation of insulin/insulin-like growth factor signaling (IIS) is associated with altered nutritional and metabolic states. The Drosophila genome encodes eight insulin-like peptides, whose activity is regulated by a group of secreted factors, including Ecdysone-inducible gene L2 (ImpL2), which...

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Detalles Bibliográficos
Autores principales: Gumeni, Sentiljana, Lamprou, Maria, Evangelakou, Zoi, Manola, Maria S., Trougakos, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670064/
https://www.ncbi.nlm.nih.gov/pubmed/37998385
http://dx.doi.org/10.3390/cells12222650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670064/
https://www.ncbi.nlm.nih.gov/pubmed/37998385
http://dx.doi.org/10.3390/cells12222650

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