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Introduction of Androgen Receptor Targeting shRNA Inhibits Tumor Growth in Patient-Derived Prostate Cancer Xenografts

Patient-derived xenograft (PDX) models have been established as important preclinical cancer models, overcoming some of the limitations associated with the use of cancer cell lines. The utility of prostate cancer PDX models has been limited by an inability to genetically manipulate them in vivo and...

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Detalles Bibliográficos
Autores principales: Thomas, Patrick B., Alinezhad, Saeid, Joshi, Andre, Sweeney, Katrina, Tse, Brian W. C., Tevz, Gregor, McPherson, Stephen, Nelson, Colleen C., Williams, Elizabeth D., Vela, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670201/
https://www.ncbi.nlm.nih.gov/pubmed/37999103
http://dx.doi.org/10.3390/curroncol30110683