Lysine Demethylase KDM2A Promotes Proteasomal Degradation of TCF/LEF Transcription Factors in a Neddylation-Dependent Manner

Canonical Wnt signaling is essential for a plethora of biological processes ranging from early embryogenesis to aging. Malfunctions of this crucial signaling pathway are associated with various developmental defects and diseases, including cancer. Although TCF/LEF transcription factors (TCF/LEFs) ar...

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Detalles Bibliográficos
Autores principales: Šopin, Tijana, Liška, František, Kučera, Tomáš, Cmarko, Dušan, Vacík, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670284/
https://www.ncbi.nlm.nih.gov/pubmed/37998355
http://dx.doi.org/10.3390/cells12222620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670284/
https://www.ncbi.nlm.nih.gov/pubmed/37998355
http://dx.doi.org/10.3390/cells12222620

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