SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage

Cells respond to DNA damage by activating a complex array of signaling networks, which include the AMPK and mTOR pathways. After DNA double-strand breakage, ATM, a core component of the DNA repair system, activates the AMPK-TSC2 pathway, leading to the inhibition of the mTOR cascade. Recently, we sh...

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Detalles Bibliográficos
Autores principales: Lepore Signorile, Martina, Sanese, Paola, Di Nicola, Elisabetta, Fasano, Candida, Forte, Giovanna, De Marco, Katia, Disciglio, Vittoria, Latrofa, Marialaura, Pantaleo, Antonino, Varchi, Greta, Del Rio, Alberto, Grossi, Valentina, Simone, Cristiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670288/
https://www.ncbi.nlm.nih.gov/pubmed/37998381
http://dx.doi.org/10.3390/cells12222644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670288/
https://www.ncbi.nlm.nih.gov/pubmed/37998381
http://dx.doi.org/10.3390/cells12222644

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