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LGR5 Expression Predicting Poor Prognosis Is Negatively Correlated with WNT5A in Colon Cancer

WNT/β-catenin signaling is essential for colon cancer development and progression. WNT5A (ligand of non-canonical WNT signaling) and its mimicking peptide Foxy5 impair β-catenin signaling in colon cancer cells via unknown mechanisms. Therefore, we investigated whether and how WNT5A signaling affects...

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Detalles Bibliográficos
Autores principales: Mehdawi, Lubna M., Ghatak, Souvik, Chakraborty, Payel, Sjölander, Anita, Andersson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670301/
https://www.ncbi.nlm.nih.gov/pubmed/37998393
http://dx.doi.org/10.3390/cells12222658