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mTOR Inhibitor Rapalink-1 Prevents Ethanol-Induced Senescence in Endothelial Cells

The cardiovascular risk factors, including smoking, ethanol, and oxidative stress, can induce cellular senescence. The senescent cells increase the expression and release of pro-inflammatory molecules and matrix metalloproteinase (MMPs). These pro-inflammatory molecules and MMPs promote the infiltra...

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Detalles Bibliográficos
Autores principales: Zhou, Huakang, Li, Xuanchen, Rana, Majeed, Cornelius, Jan Frederick, Khan, Dilaware, Muhammad, Sajjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670449/
https://www.ncbi.nlm.nih.gov/pubmed/37998344
http://dx.doi.org/10.3390/cells12222609