Understanding the Role of Activation Loop Mutants in Drug Efficacy for FLT3-ITD

SIMPLE SUMMARY: In this study, we investigated FLT3, a protein that plays a vital role in the development of early blood cells. FLT3 often undergoes changes that contribute to the onset of a blood cancer known as acute myeloid leukemia (AML). We employed sophisticated computational techniques to exa...

Descripción completa

Detalles Bibliográficos
Autores principales: Kazi, Julhash U., Al Ashiri, Lina, Purohit, Rituraj, Rönnstrand, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670458/
https://www.ncbi.nlm.nih.gov/pubmed/38001685
http://dx.doi.org/10.3390/cancers15225426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670458/
https://www.ncbi.nlm.nih.gov/pubmed/38001685
http://dx.doi.org/10.3390/cancers15225426

Ejemplares similares