Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy

Oxidative stress and impaired mitophagy are the hallmarks of cardiomyocyte senescence. Specifically, a decrease in mitophagic flux leads to the accumulation of damaged mitochondria and the development of senescence through increased ROS and other mediators. In this study, we describe the preventive...

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Detalles Bibliográficos
Autores principales: Foglio, Eleonora, D’Avorio, Erica, Vitiello, Laura, Masuelli, Laura, Bei, Roberto, Pacifici, Francesca, Della-Morte, David, Mirabilii, Simone, Ricciardi, Maria Rosaria, Tafuri, Agostino, Garaci, Enrico, Russo, Matteo Antonio, Tafani, Marco, Limana, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670650/
https://www.ncbi.nlm.nih.gov/pubmed/37998340
http://dx.doi.org/10.3390/cells12222605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670650/
https://www.ncbi.nlm.nih.gov/pubmed/37998340
http://dx.doi.org/10.3390/cells12222605

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