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Simvastatin Attenuates Areca Nut Extract-Induced Subdermal Fibrosis in Mice by Targeting TGF-β Signaling Pathways

Oral submucous fibrosis (OSMF) is a chronic inflammatory disease and a potentially malignant oral disorder, characterized by fibrosis of the oral mucosa. TGF-β signaling pathways have been implicated in the development of OSMF, with areca nut extract (ANE) contributing to the disease progression. Si...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Hua, Lin, Ching-Ping, Chen, Yuk-Kwan, Hsiao, Yu-Fang, Wang, Yan-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670689/
https://www.ncbi.nlm.nih.gov/pubmed/37998719
http://dx.doi.org/10.3390/cimb45110542