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A New Synthetic Curcuminoid Displays Antitumor Activities in Metastasized Melanoma

Aim: The semisynthetic derivatives MePip-SF5 and isogarcinol, which are aligned with the natural products curcumin and garcinol, were tested for their antitumor effects in a preclinical model of pulmonary melanoma metastasis. Methods and results: MePip-SF5 was almost five times more effective in inh...

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Detalles Bibliográficos
Autores principales: Kaps, Leonard, Klefenz, Adrian, Traenckner, Henry, Schneider, Paul, Andronache, Ion, Schobert, Rainer, Biersack, Bernhard, Schuppan, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670708/
https://www.ncbi.nlm.nih.gov/pubmed/37998354
http://dx.doi.org/10.3390/cells12222619