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Inhibition of EIF2α Dephosphorylation Decreases Cell Viability and Synergizes with Standard-of-Care Chemotherapeutics in Head and Neck Squamous Cell Carcinoma

SIMPLE SUMMARY: Head and neck squamous cell carcinoma (HNSCC) arises in the mucosal membranes in the head and neck and constitutes 3.9% of new cancer cases annually. Its pathogenesis is stepwise; the formation of invasive and metastatic cancer is preceded by premalignant mucosal changes. With little...

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Detalles Bibliográficos
Autores principales: Cyran, Anna M., Kleinegger, Florian, Nass, Norbert, Naumann, Michael, Haybaeck, Johannes, Arens, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670742/
https://www.ncbi.nlm.nih.gov/pubmed/38001610
http://dx.doi.org/10.3390/cancers15225350