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HLA-Homozygous iPSC-Derived Mesenchymal Stem Cells Rescue Rotenone-Induced Experimental Leber’s Hereditary Optic Neuropathy-like Models In Vitro and In Vivo

Background: Mesenchymal stem cells (MSCs) hold promise for cell-based therapy, yet the sourcing, quality, and invasive methods of MSCs impede their mass production and quality control. Induced pluripotent stem cell (iPSC)-derived MSCs (iMSCs) can be infinitely expanded, providing advantages over con...

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Detalles Bibliográficos
Autores principales: Tsai, En-Tung, Peng, Shih-Yuan, Wu, You-Ren, Lin, Tai-Chi, Chen, Chih-Ying, Liu, Yu-Hao, Tseng, Yu-Hsin, Hsiao, Yu-Jer, Tseng, Huan-Chin, Lai, Wei-Yi, Lin, Yi-Ying, Yang, Yi-Ping, Chiou, Shih-Hwa, Chen, Shih-Pin, Chien, Yueh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670753/
https://www.ncbi.nlm.nih.gov/pubmed/37998352
http://dx.doi.org/10.3390/cells12222617