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The Force-Dependent Mechanism of an Integrin α4β7–MAdCAM-1 Interaction

The interaction between integrin α4β7 and mucosal vascular addressin cell-adhesion molecule-1 (MAdCAM-1) facilitates the adhesion of circulating lymphocytes to the surface of high endothelial venules in inflammatory bowel diseases (IBDs). Lymphocyte adhesion is a multistep cascade involving the teth...

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Detalles Bibliográficos
Autores principales: Su, Youmin, Luo, Zhiqing, Sun, Dongshan, Yang, Bishan, Li, Quhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670920/
https://www.ncbi.nlm.nih.gov/pubmed/38003252
http://dx.doi.org/10.3390/ijms242216062