Dependency of B-Cell Acute Lymphoblastic Leukemia and Multiple Myeloma Cell Lines on MEN1 Extends beyond MEN1–KMT2A Interaction

Menin/MEN1 is a scaffold protein that participates in proliferation, regulation of gene transcription, DNA damage repair, and signal transduction. In hematological malignancies harboring the KMT2A/MLL1 (MLLr) chromosomal rearrangements, the interaction of the oncogenic fusion protein MLLr with MEN1...

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Detalles Bibliográficos
Autores principales: Wolffhardt, Tatjana Magdalena, Ketzer, Franz, Telese, Stefano, Wirth, Thomas, Ushmorov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670986/
https://www.ncbi.nlm.nih.gov/pubmed/38003662
http://dx.doi.org/10.3390/ijms242216472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670986/
https://www.ncbi.nlm.nih.gov/pubmed/38003662
http://dx.doi.org/10.3390/ijms242216472

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