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Dependency of B-Cell Acute Lymphoblastic Leukemia and Multiple Myeloma Cell Lines on MEN1 Extends beyond MEN1–KMT2A Interaction

Menin/MEN1 is a scaffold protein that participates in proliferation, regulation of gene transcription, DNA damage repair, and signal transduction. In hematological malignancies harboring the KMT2A/MLL1 (MLLr) chromosomal rearrangements, the interaction of the oncogenic fusion protein MLLr with MEN1...

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Detalles Bibliográficos
Autores principales:	Wolffhardt, Tatjana Magdalena, Ketzer, Franz, Telese, Stefano, Wirth, Thomas, Ushmorov, Alexey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670986/ https://www.ncbi.nlm.nih.gov/pubmed/38003662 http://dx.doi.org/10.3390/ijms242216472

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