Pan-Inhibition of Protein Disulfide Isomerase Caused Cell Death through Disrupting Cellular Proteostasis in Pancreatic Ductal Adenocarcinoma Cells

The protein disulfide isomerase (PDI) family is a group of thioredoxin endoplasmic reticulum (ER)-resident enzymes and molecular chaperones that play crucial roles in the correct folding of proteins. PDIs are upregulated in multiple cancer types and are considered a novel target for cancer therapy....

Descripción completa

Detalles Bibliográficos
Autores principales: Hung, Ching-Sheng, Lee, Kun-Lin, Huang, Wei-Jan, Su, Fang-He, Liang, Yu-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671009/
https://www.ncbi.nlm.nih.gov/pubmed/38003657
http://dx.doi.org/10.3390/ijms242216467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671009/
https://www.ncbi.nlm.nih.gov/pubmed/38003657
http://dx.doi.org/10.3390/ijms242216467

Ejemplares similares