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Pan-Inhibition of Protein Disulfide Isomerase Caused Cell Death through Disrupting Cellular Proteostasis in Pancreatic Ductal Adenocarcinoma Cells

The protein disulfide isomerase (PDI) family is a group of thioredoxin endoplasmic reticulum (ER)-resident enzymes and molecular chaperones that play crucial roles in the correct folding of proteins. PDIs are upregulated in multiple cancer types and are considered a novel target for cancer therapy....

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Detalles Bibliográficos
Autores principales:	Hung, Ching-Sheng, Lee, Kun-Lin, Huang, Wei-Jan, Su, Fang-He, Liang, Yu-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671009/ https://www.ncbi.nlm.nih.gov/pubmed/38003657 http://dx.doi.org/10.3390/ijms242216467

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